EVOXAC® (cevimeline HCl) For Dry-Mouth Symptoms Associated With Sjögren's Syndrome

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Why EVOXAC?

EVOXAC works systemically (in the body) to stimulate your body's natural flow of saliva to help with eating and speaking.

In clinical studies, 53% to 76% of patients reported their dry-mouth symptoms as "better". Patients were evaluated by a measure called global improvement, which is defined as a response of "better" to the question, "Please rate the overall condition of your dry mouth now compared with how you felt before starting treatment in this study." Patients also had the option of selecting "worse" or "no change" as answers.

Patients also reported significant improvement in oral comfort and function. Significant improvement in the symptoms of dry mouth was observed in 2 of 3 clinical trials vs. placebo. However, there was a higher placebo response rate in one 12-week study.

EVOXAC is a convenient treatment option. The standard dose of EVOXAC (30 mg) is taken three times per day compared to the four times a day regimen of pilocarpine HCl.*

*
Dosing information for EVOXAC and pilocarpine HCl is based on respective prescribing information and not intended as a clinical comparsion of efficacy or safety among those products.

Doctor Discussion Guide

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Dry Mouth & Sjögren's Syndrome

Learn about the effects of dry mouth associated with Sjögren's syndrome. Read more

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