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Symptoms Of Dry Mouth Associated With Sjögren's Syndrome

It's important to recognize the signs of dry mouth associated with Sjögren's syndrome. (sho'grenz) Please download the latest version of the Free Flash Player Plugin to view this site Diminished salivary secretion deprives the oral cavity of protection, making it vulnerable to various physical, chemical, and microbial insults, which may result in oral damage.^1,2

Dry-mouth symptoms can be severely bothersome for some patients, but patients rarely associate these symptoms with an illness.² This is why it's important for healthcare professionals to recognize that they might be a sign of Sjögren's syndrome.³

Symptoms of dry mouth commonly experienced by Sjögren's syndrome patients can affect both health and certain daily activities.^1,4-6

Dry-mouth symptoms commonly experienced by Sjogren's syndrome patients

Due to Candida superinfection

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Important Safety Information

EVOXAC is indicated for the treatment of dry-mouth symptoms of Sjögren's syndrome.

Cevimeline HCI is contraindicated in patients with uncontrolled asthma, known hypersensitivity to the drug, and when miosis is undesirable, e.g., in acute iritis and narrow-angle (angle-closure) glaucoma
Cevimeline HCI can potentially alter cardiac conduction and heart rate and produce transient changes in hemodynamics. Cevimeline HCI should be administered with caution and under close medical supervision to patients with a history of cardiac disease, controlled asthma, chronic bronchitis, or chronic obstructive pulmonary disease
Cevimeline HCI should be administered with caution to patients taking beta-adrenergic antagonists because of the possibility of conduction disturbances and to patients with a history of nephrolithiasis or cholelithiasis
If a patient sweats excessively while taking cevimeline HCI, dehydration may develop
Caution should be advised while driving at night or performing hazardous activities in reduced lighting

Safety and effectiveness in pediatric patients have not been established
Cevimeline HCI is metabolized by the P-450 isozymes CYP2D6 and CYP3A3/4. Thus, there may be potential for interaction between cevimeline HCI and other compounds
Special care should be exercised when cevimeline HCI is taken by geriatric patients, considering the greater frequency of decreased hepatic, renal, or cardiac function
The most frequently reported adverse events associated with the pharmacologic action of a muscarinic agonist (>10% incidence) in clinical trials of cevimeline HCI were: excessive sweating, nausea, rhinitis, and diarrhea. Consult the full Prescribing Information for other adverse events

The content provided herein is for informational purposes only and does not constitute or substitute for professional medical advice, diagnosis, or treatment. Talk to your doctor for more information about your specific condition.

The photos on this site depict models, not actual patients or healthcare professionals.

Dry Mouth & Sjögren's Syndrome

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Symptoms Of Dry Mouth Associated With Sjögren's Syndrome

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Important Safety Information